In our current rig (Sprinter Van) Hubby and I each get two bins for clothes - the bins are about 16'x10"x10", one for our cycling/hiking clothes, one for everything else. We each get a smaller bin (1 cubic foot) for cycling gear like shoes, helmet, gloves, glasses, computers, lights.... We also have a drawer permanently packed with puffy coats, gloves, hats, and raincoats so we never forget them and a drawer for our slippers, flip flops, and camp shoes. Then we get whatever shoes we happen to be wearing when we leave the house. This works out pretty well for us, and in truth I usually return home with more than half the clothes I brought unworn!
I also have bins with the toiletries and food staples already packed. I bring them in the house if we won't be camping for a while so they don't get too hot baking in the driveway.
So, on departure day, I pack the bins, the fridge, the dogs, the husband, and the espresso maker, and top off the water tank and we're good to go!